Name | EGFR/ErbB-2/ErbB-4 Inhibitor - CAS 881001-19-0 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 324840 |
Cas Number | 881001-19-0 |
Formula | C₁₇H₁₁ClFN₅O•2.5H₂O |
Purity | ≥95% by HPLC |
Description | A cell-permeable, ATP-binding site-targeting alkynamidopyrimidine compound that acts as a potent and irreversible inhibitor of erbB activities (IC 50 = 0.3, 1.1, and 0.5 nM for erbB-1, erbB-2, and erbB-4, respectively) |
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