HIF-2α Translation Inhibitor - CAS 882268-69-1 - Calbiochem
| Name | HIF-2α Translation Inhibitor - CAS 882268-69-1 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 400087 |
| Cas Number | 882268-69-1 |
| Formula | C₉H₉N₃O₄S₂ |
| Purity | ≥95% (sum of two isomers) |
| Description | A cell-permeable thienylhydrazone compound that suppresses the translation of cellular HIF-2α message by enhancing the binding of IRP1 (Iron-Regulatory Protein 1) to the IRE (Iron-Responsive Element) region at the 5' UTR of the HIF-2α mRNA, exhibiting otherwise no effects toward the transcription of HIF-2α mRNA or the stability of HIF-2α mRNA and protein |
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