Ras-Net (Elk-3) Pathway Inhibitor, XRP44X - CAS 729605-21-4 - Calbiochem

Name Ras-Net (Elk-3) Pathway Inhibitor, XRP44X - CAS 729605-21-4 - Calbiochem
Supplier EMD Millipore
Catalog 480150
Cas Number 729605-21-4
Formula C₂₁H₂₁ClN₄O
Purity ≥98% by HPLC
Description A cell-permeable pyrazole compound that is shown to prevent in vitro tubulin polymerization (IC 50 = 0.2 µM) by targeting Colchicine (Cat. No. 234115 ) binding site (Kd = 0.3 µM) in cell-free assays and induce blebs formation in HUVEC cultures by perturbing both tubulin microtubles and actin cytoskeleton structures
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