Name | Ras-Net (Elk-3) Pathway Inhibitor, XRP44X - CAS 729605-21-4 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 480150 |
Cas Number | 729605-21-4 |
Formula | C₂₁H₂₁ClN₄O |
Purity | ≥98% by HPLC |
Description | A cell-permeable pyrazole compound that is shown to prevent in vitro tubulin polymerization (IC 50 = 0.2 µM) by targeting Colchicine (Cat. No. 234115 ) binding site (Kd = 0.3 µM) in cell-free assays and induce blebs formation in HUVEC cultures by perturbing both tubulin microtubles and actin cytoskeleton structures |
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