Meriolin 3 - CAS 954143-48-7 - Calbiochem

• Supplier: EMD Millipore
• Catalog: 445821
• Cas Number: 954143-48-7
• Formula: C₁₂H₁₁N₅O
• Purity: ≥95% by HPLC
• Description: A cell-permeable, ATP site-targeting azaindolopyrimidine compound that is reported to inhibit the kinase activity of CDK9/cyclin T, CDK2/cyclin A, CDK1/cyclin B, CDK5/p25 (IC 50 = 6, 11, 170, 170 nM, respectively), DYRK1A, CKIδ/ε, GSK-3α/β (IC 50 = 29, 200, and 230 nM, respectively), as well as CDK3/cyclin E, CDK4/cyclin D1, CDK6/cyclin D1, CDK7/cyclin H, and FLT3 (IC 50 <400 nM), while showing much reduced activity agasint 21 other kinases (IC 50 >1 µM)

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