MK-2 Inhibitor IV, MK-25 - Calbiochem

Name MK-2 Inhibitor IV, MK-25 - Calbiochem
Supplier EMD Millipore
Catalog 475964
Formula C₂₇H₂₅ClN₄O₂,HCl
Purity ≥95% by HPLC
Description A cell-permeable furanylcarboxamide compound that acts as a potent, reversible and non-ATP-competitive inhibitor of MK-2/MAPKAP-K2 activity (IC 50 = 110 nM; EC 50 = 350 nM for pHSP27 in IL-1β-stimulated SW1353 cells) with excellent selectivity over 150 kinases (% activity inhibition at 10 µM against human CK2, Haspin, Arg and CK1γ3 = 40, 40, 42 and > 70, respectively)
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