Smac- N7 Peptide

Name Smac- N7 Peptide
Supplier EMD Millipore
Catalog 567370
Formula Suppliedasatrifluoroacetatesalt.
Purity ≥95% by HPLC
Description A peptide that contains the N-terminal seven residues of Smac (Second mitochondria-derived activator of caspases, also known as DIABLO) and promotes pro-caspase-3 activation at ~10 µM. Reported to bind to the BIR2 and BIR3 (baculovirus IAP repeat) domains of XIAP (X-linked inhibitor of apoptosis proteins) (K d = ~800 nM)
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