VEGFR2 Kinase Inhibitor VII, SKLB1002 - Calbiochem

Name VEGFR2 Kinase Inhibitor VII, SKLB1002 - Calbiochem
Supplier EMD Millipore
Catalog 676505
Formula C₁₃H₁₂N₄O₂S₂
Purity ≥98% by HPLC
Description A cell-permeable quinazoline that acts as a potent, ATP-binding site-targeting, VEGFR2-selective inhibitor (IC 50 = 32 nM), while exhibiting much reduced potency against c-kit, Ret, FMS, PDGFRα, and Aurora A (IC 50 = 0.62, 2.5, 2.9, 3.1, and 3.9 µM, respectively) and little or no activity against 11 other kinases (IC 50 >10 µM)
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