Name | VEGFR2 Kinase Inhibitor VII, SKLB1002 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 676505 |
Formula | C₁₃H₁₂N₄O₂S₂ |
Purity | ≥98% by HPLC |
Description | A cell-permeable quinazoline that acts as a potent, ATP-binding site-targeting, VEGFR2-selective inhibitor (IC 50 = 32 nM), while exhibiting much reduced potency against c-kit, Ret, FMS, PDGFRα, and Aurora A (IC 50 = 0.62, 2.5, 2.9, 3.1, and 3.9 µM, respectively) and little or no activity against 11 other kinases (IC 50 >10 µM) |
Supplier Page | Shop |