HMTase Inhibitor VI, BRD4770 - Calbiochem

Name HMTase Inhibitor VI, BRD4770 - Calbiochem
Supplier EMD Millipore
Catalog 382194
Formula C₂₅H₂₃N₃O₃
Purity ≥98% by HPLC
Description A cell-permeable analog of the amino-benzimidazolo BIX-01338 (Cat. No. 539212 ) and the methylester prodrug of BRD9539 that acts as an SAM-competitive inhibitor against PRC2 and G9a (IC 50 ≤6.3 µM) histone methyltransferase activities, displaying little effect toward 10 other HMTases, 9 HDACs, and 100 cellular kinases
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