PDE10A Inhibitor, Cpd15 - Calbiochem
| Name | PDE10A Inhibitor, Cpd15 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 513050 |
| Formula | C₁₈H₁₆ClN₅O |
| Purity | ≥98% by HPLC |
| Description | A cell-permeable pyrazoloquinoline compound that acts as a potent phosphodiesterase 10A inhibitor ( K i ≤5 nM against human PDE10A-catalyzed cAMP hydrolysis), while exhibiting >500-fold selectivity over other human PDEs 1-11 and much reduced or little activity against CYP3A4 (IC 50 = 7.9 and >20 µM, respectively, with or without preincubation) as well as a panel of 23 kinases (IC 50 >30 µM) |
| Supplier Page | Shop |
Product images
