EGF/FGF/PDGF Receptor Tyrosine Kinase Inhibitor - CAS 1135256-66-4 - Calbiochem

Name EGF/FGF/PDGF Receptor Tyrosine Kinase Inhibitor - CAS 1135256-66-4 - Calbiochem
Supplier EMD Millipore
Catalog 324841
Cas Number 1135256-66-4
Formula C₁₈H₁₈Cl₂N₆O
Purity ≥ 97% by HPLC
Description A cell-permeable and reversible protein tyrosine kinase inhibitor that inhibits human FGFR-1, PDGFR-β, c-Src, and EGFR (IC 50 = 0.15, 0.18, 1.76, and 5.47 µM, respectively), while exhibiting little activity against InsR, PKC, or CDK4/Cyclin D1 (IC 50 >50 µM)
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