VEGFR Tyrosine Kinase Inhibitor IV - CAS 475108-18-0 - Calbiochem

Name VEGFR Tyrosine Kinase Inhibitor IV - CAS 475108-18-0 - Calbiochem
Supplier EMD Millipore
Catalog 676483
Cas Number 475108-18-0
Formula C₂₂H₁₉ClN₄O₅•H₂O
Purity ≥95% by HPLC
Description A cell-permeable quinoline-urea compound that potently inhibits the kinase activity of VEGFR (IC 50 = 30, 6.5, and 15 nM for VEGFR-1,-2, and -3, respectively), EphB2, PDGFR-α, PDGFR-β, c-Kit, and Tie-2 (IC 50 = 24, 40, 49, 78, and 78 nM, respectively)
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