Name | γ-Secretase Inhibitor XII - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 565773 |
Formula | C₂₀H₃₀N₂O₄ |
Purity | ≥95% by HPLC |
Description | A cell-permeable, reversible dipeptide aldehyde that reduces amyloid-β protein (Aβ) production by blocking γ-secretase activity in vitro (Aβ 40 IC 50 = 7.9 µM; Aβ 42 IC 50 = 7.6 µM) and in cultured cells that stably over-express APP695 (Aβ 40 IC 50 = 11.5 µM; Aβ 42 IC 50 = 8.3 µM) |
Supplier Page | Shop |