JNK Inhibitor XI, BI-87G3 - CAS 2207-44-5 - Calbiochem
| Name | JNK Inhibitor XI, BI-87G3 - CAS 2207-44-5 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 420142 |
| Cas Number | 2207-44-5 |
| Formula | C₁₀H₅N₃O₂S₃ |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable benzothiazole compound that inhibits JNK kinase activity (IC 50 = 1.8 µM against ATF2 phosphorylation by JNK1) by competing with substrate binding (IC 50 = 0.16 µM against pepJIP1 binding to JNK2), while exhibiting much reduced activity toward two other kinases (IC 50 >100 µM against p38α and Akt) and two other proteases (IC 50 >50 and >100 µM, respectively, against furin and LF) |
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