Raf Kinase Inhibitor IV - CAS 303727-31-3 - Calbiochem
| Name | Raf Kinase Inhibitor IV - CAS 303727-31-3 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 553014 |
| Cas Number | 303727-31-3 |
| Formula | C₂₀H₁₄ClN₃O |
| Purity | ≥97% by HPLC |
| Description | A cell-permeable triarylimidazole compound that acts as a reversible, ATP-competitive, and highly potent inhibitor of Raf kinase (IC 50 = 10 nM & K d = 2.4 nM for B-raf) with 7-, 30-, and 70-fold selectivity over p38α, GSK-3β, and Lck, respectively |
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