Haspin Kinase Inhibitor, CHR-6494 - CAS 1333377-65-3 - Calbiochem
| Name | Haspin Kinase Inhibitor, CHR-6494 - CAS 1333377-65-3 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 372040 |
| Cas Number | 1333377-65-3 |
| Formula | C₁₆H₁₆N₆ |
| Purity | ≥98% by HPLC |
| Description | A cell-permeable indazolylimidazopyridazinamine compound that acts as a potent and reversible inhibitor of histone kinase haspin activity (IC 50 = 2 nM) with moderate selectivity over TrkA, GSK-3β, PIM1, Cdk1/B and Cdk2/A (% inhibition at 100 nM = 58, 48, 36, 34 and 33, respectively) among a panel of 27-kinases |
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