JMJD Histone Demethylase Inhibitor IV, Methylstat - CAS 1310877-95-2 - Calbiochem

Name JMJD Histone Demethylase Inhibitor IV, Methylstat - CAS 1310877-95-2 - Calbiochem
Supplier EMD Millipore
Catalog 420203
Cas Number 1310877-95-2
Formula C₂₈H₃₁N₃O6
Purity ≥96% by HPLC
Description A methyl ester prodrug of in vitro active N-hydroxybutenoic acid compound (Cat. No. 420202) that is shown to preferentially induce hypermethylation of histone proteins (EC 50 for H3K4me3 and H3K9me3 = 10.3 and 8.6 µM in KYSE150 cells, and 6.7 and 6.3 µM in MCF7 cells, respectively), and arrests cell growth
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