IGF-1R Inhibitor, PPP - CAS 477-47-4 - Calbiochem
| Name | IGF-1R Inhibitor, PPP - CAS 477-47-4 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 407247 |
| Cas Number | 477-47-4 |
| Formula | C₂₂H₂₂O₈ |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable, reversible, potent, substrate competitive, and specific inhibitor of IGF-1R both in vitro (IC 50 = 1 nM in cell-free kinase assay; ≤60 nM and for cell viability and receptor autophosphorylation in melanoma cell lines) and in vivo (complete inhibition of IGF-1R-dependent tumor cell growth at 20 mg/kg/12 hr i.p |
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