JAK2 Inhibitor V, Z3 - CAS 195371-52-9 - Calbiochem
| Name | JAK2 Inhibitor V, Z3 - CAS 195371-52-9 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 420141 |
| Cas Number | 195371-52-9 |
| Formula | C₂₃H₂₄N₂O |
| Purity | ≥97% by HPLC |
| Description | A cell-permeable pyridinylbutanone compound that inhibits cellular autophosphorylation of both the wild-type Jak2 and the constitutively active V167F mutant (IC 50 = 15 & 28 µM, respectively, with WT- & V617F-transfected BSC-40 cells), while exhiting no effect against cellular Tyk2 autophosphorylation in COS cells or c-Src kinase in cell-free kinase assays |
| Supplier Page | Shop |
Product images
