Autophagy Inducer, STF-62247 - CAS 315702-99-9 - Calbiochem
| Name | Autophagy Inducer, STF-62247 - CAS 315702-99-9 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 189497 |
| Cas Number | 315702-99-9 |
| Formula | C₁₅H₁₃N₃S |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable autophagy inducer that selectively induces non-apoptotic cell death in VHL- (von Hippel-Lindau) deficient, but not VHL-expressing, renal carcinoma cells both in vitro (IC 50 = 0.625 and 16 µM in RCC4 and RCC4/VHL killing, respectively) and in mice in vivo (>90% 786-O tumor growth suppression; 8 mg/kg via daily i.p.) |
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