ATM/ATR Kinase Inhibitor - CAS 905973-89-9 - Calbiochem

Name ATM/ATR Kinase Inhibitor - CAS 905973-89-9 - Calbiochem
Supplier EMD Millipore
Catalog 118501
Cas Number 905973-89-9
Formula C₂₃H₁₈Cl₃FN₄O₃S
Purity ≥95% by HPLC
Description A cell-permeable thiourea compound that selectively inhibits the kinase activity of ATM and ATR (IC 50 ~ 200 nM) without significant effect against other PIKK family members (PI3K, mTOR, and DNA-PK) or kinases that are known to phosphorylate p53 (ERK, CK1, Cdk2, JNK, PKC, CAK, Chk1, PKR, and p38)
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