Wnt Pathway Inhibitor XI, CCT036477 - CAS 305372-78-5 - Calbiochem
| Name | Wnt Pathway Inhibitor XI, CCT036477 - CAS 305372-78-5 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 681674 |
| Cas Number | 305372-78-5 |
| Formula | C₂₁H₁₈ClN₃ |
| Purity | ≥95% by 1H NMR |
| Description | A cell-permeable indole derivative that acts as an inhibitor of Wnt signaling and exhibits an inhibitory effect in a reporter cell line (IC 50 = 4.6 µM) and demonstrates growth inhibition in multiple cancer cell lines, not by altering β-catenin accumulation but by blocking transcription at the β-catenin level |
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