β-Glucuronidase Inhibitor - Calbiochem

Name β-Glucuronidase Inhibitor - Calbiochem
Supplier EMD Millipore
Catalog 347423
Formula C₂₃H₂₇N₃O₃S
Purity ≥99% by HPLC
Description An orally bioavailable trisubstituted thiourea compound that acts as a potent, uncompetitive and reversible inhibitor of bacterial β-glucuronidase activity (IC 50 = 283 nM; k cat /K m = 0.0987 s -1 µM -1 ; K i = 164 nM in vitro assays against E coli β-glucuronidase; EC 50 = 17.7 nM in β-glucuronidase expressing HB101 cells) with excellent selectivity over mammalian β-glucuronidases
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