β-Catenin/Tcf Inhibitor II, PKF118-310 - Calbiochem
| Name | β-Catenin/Tcf Inhibitor II, PKF118-310 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 219331 |
| Formula | C₇H₇N₅O₂ |
| Purity | ≥95% by HPLC |
| Description | A synthetic cell-permeable actinobacteria pyrimidotriazine-dione that selectively disrupts β-catenin-Tcf4 interaction (IC 50 = 0.8 µM in cell-free binding assays) and inhibits β-catenin-regulated cellular transcription activity (IC 50 = 0.3 µM in HCT116-based reporter assays) |
| Supplier Page | Shop |
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