Name | Wee1 Inhibitor - CAS 622855-37-2 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 681640 |
Cas Number | 622855-37-2 |
Formula | C₂₀H₁₁ClN₂O₃ |
Purity | ≥97% by HPLC |
Description | A pyrrolocarbazole compound that acts as a poten, ATP-binding site-targeting inhibitor of Wee1 (IC 50 = 11 nM) in an ATP-competitive manner and displays ~40-fold selectivity over the related checkpoint kinase Chk1 (IC 50 = 440 nM). |
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