Ubiquitin E1 Inhibitor, PYR-41 - Calbiochem
| Name | Ubiquitin E1 Inhibitor, PYR-41 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 662105 |
| Formula | C₁₇H₁₃N₃O₇•3H₂O |
| Purity | ≥90% by HPLC (sum of two isomers) |
| Description | A cell-permeable pyrazone compound that irreversibly (presumably via covalent modification) inhibits ubiquitin-activating enzyme E1 activity (IC 50 <10 µM in cell-free E1 ubiquitination reactions), while exhibiting little or no activity against E3, E2, or caspase enzymatic activity |
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