MMP-12 Inhibitor, MMP408 - CAS 1258003-93-8 - Calbiochem
| Name | MMP-12 Inhibitor, MMP408 - CAS 1258003-93-8 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 444291 |
| Cas Number | 1258003-93-8 |
| Formula | C₁₉H₂₀N₂O₇S |
| Purity | ≥94% by HPLC |
| Description | A dibenzofuranylsulfanamido-valine compound that acts as a potent, active site zinc-targeting, MMP-12-selective inhibitor (IC 50 = 2 nM against human MMP-12) with much weaker activity against MMP-12 from mouse/rat/sheep species (IC 50 = 160, 320 and 22.3 nM, respectively) or human MMP-3/13/14 (IC 50 = 351, 120 and 1100 nM , respectively), and practically ineffective toward human Agg-1/2 (IC 50 >5 µM), TACE (IC 50 >25 µM), and MMP-1/7 (IC 50 >6 µM) |
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