InSolution™ IKK-2 Inhibitor IV - Calbiochem

• Supplier: EMD Millipore
• Catalog: 401484
• Formula: A10mM(500µg/179µl)solutionofIKK-2InhibitorIV(
• Purity: ≥95% by HPLC
• Description: IKK-2 Inhibitor IV (Cat. No. 401481) supplied in DMSO. A cell-permeable and potent inhibitor of IKK-2 (IC 50 = 18 nM) that exhibits selectivity over IKK-1, JNK, and p38 MAPK. Inhibits TNF-α production in human monocytes (IC 50 in the range of 0.15-2.5 µM) and blocks IL-8 and IL-6 production by synovial fibroblasts (IC 50 = 100 nM)

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