SIRT2 Inhibitor II, AK-1 - CAS 330461-64-8 - Calbiochem

Name SIRT2 Inhibitor II, AK-1 - CAS 330461-64-8 - Calbiochem
Supplier EMD Millipore
Catalog 566331
Cas Number 330461-64-8
Formula C₁₉H₂₁N₃O₅S
Purity >95% by HPLC
Description A cell permeable, benzylsulfonamide that inhibits SIRT2 activity (IC 50 = 12.5 µM through enzymatic assay) by targeting the SIRT2 nicotinamide binding site, but may also target SIRT1 and SIRT3 (IC 50 >40 µM) with much less potency
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