IKK-2 Inhibitor IV - CAS 507475-17-4 - Calbiochem
| Name | IKK-2 Inhibitor IV - CAS 507475-17-4 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 401481 |
| Cas Number | 507475-17-4 |
| Formula | C₁₂H₁₀FN₃O₂S |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable, reversible, ATP-competitive, and potent inhibitor of IKK-2 (IC 50 = 18 nM) that exhibits selectivity over IKK-1, JNK, and p38 MAPK. Inhibits TNF-α production in human monocytes (IC 50 in the range of 0.15-2.5 µM) and blocks IL-8 and IL-6 production by synovial fibroblasts (IC 50 = 100 nM) |
| Supplier Page | Shop |
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