PTP Inhibitor XVIII - CAS 1229246-07-4 - Calbiochem
| Name | PTP Inhibitor XVIII - CAS 1229246-07-4 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 540216 |
| Cas Number | 1229246-07-4 |
| Formula | C₁₉H₁₀BrF₆NO₃S |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable thiazolidinedione compound that is shown to inhibit the enzymatic activity of PTP1B, SHP-1, YOP, TC-PTP, and YPTP1 (IC 50 = 5, 5.8, 6, 16, and 18 µM, respectively), but not that of LAR even at concentrations as high as 100 µM. Also reported to activate cellular PPAR with an comparable potency seen with troglitazone (Cat. No. 648469) |
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