PI 3-Kδ/γ Inhibitor XV, SW-14 - Calbiochem
| Name | PI 3-Kδ/γ Inhibitor XV, SW-14 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 526560 |
| Formula | C₂₈H₂₂FN₇O₂ |
| Purity | >95% by HPLC |
| Description | A cell permeable, ATP competitive tolyl quinazolinone inhibitor of PI 3-Kδ/γ that displays 70-fold selectivity over PI 3-Kβ and 900-fold selectivity over PI 3-Kα in enzymatic assays with an IC 50 = 9 nM for PI3Kδ and 21 nM for PI 3-Kγ and in a cell-based assay with an EC 50 = 132 nM for PI 3-Kδ and 4.5 nM for PI 3-K γ |
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