Name | CBP-CREB Interaction Inhibitor - CAS 92-78-4 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 217505 |
Cas Number | 92-78-4 |
Formula | C₁₇H₁₂ClNO₂ |
Purity | ≥97% by HPLC |
Description | A cell-permeable naphthamide compound that effectively blocks the interaction between the KIX domain of CBP and the KID domain of CREB in HEK293T-based and cell-free Renilla luciferase (RLuc) complementation assays (IC 50 = 2.26 and 2.9 µM, respectively) by directly binding to CBP's KIX domain ( K d ~8.6 µM using a recombinant KIX) |
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