STAT3 Inhibitor XX, inS3-54 - Calbiochem
| Name | STAT3 Inhibitor XX, inS3-54 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 531546 |
| Formula | C₂₄H₁₆N₂O₅ |
| Purity | ≥98% by HPLC |
| Description | A cell permeable pyrrolonyl benzoic acid derivative that selectively and non-covalently binds to STAT3 and inhibits its DNA binding activity in a dose and time dependent manner (IC 50 = 13.8 µM after 29 hours incubation) and reduces the expression of STAT3 dependent genes (Cyclin D1, survivin, VEGF, MMP-2, MMP-9, and Twist) in A549 and MDA-MB-231 cells |
| Supplier Page | Shop |
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