Name | Merbarone - CAS 97534-21-9 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 445800 |
Cas Number | 97534-21-9 |
Formula | C₁₁H₉N₃O₃S |
Purity | ≥95% by HPLC |
Description | A cell-permeable, anticancer drug that inhibits the catalytic activity of DNA topoisomerase II (topo II) without damaging DNA or stabilizing DNA-topo II cleavable complexes (IC 50 = 20 µM for purified mammalian topoisomerase II versus IC 50 ~200 µM for topoisomerase I) |
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