mTOR Kinase Inhibitor II, WYE-354 - CAS 1062169-56-5 - Calbiochem
| Name | mTOR Kinase Inhibitor II, WYE-354 - CAS 1062169-56-5 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 475986 |
| Cas Number | 1062169-56-5 |
| Formula | C₂₄H₂₉N₇O₅ |
| Purity | ≥98% by HPLC |
| Description | A cell-permeable pyrazolopyrimidine compound that acts as a potent and ATP-competitive mTOR inhibitor (IC 50 = 5 nM with S6K as the substrate and 100 µM ATP) with much reduced activity against PI 3-Kα or PI 3-Kγ (IC 50 = 1.89 and 7.37 µM, respectively) and little or no activity toward 24 other kinases (IC 50 >50 µM) |
| Supplier Page | Shop |
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