Pepstatin A Methyl Ester - Calbiochem

• Supplier: EMD Millipore
• Catalog: 516485
• Formula: C₃₅H₆₅N₅O₉
• Purity: ≥95% by HPLC
• Description: A cell-permeable methyl ester derivative of Pepstatin A (Cat. No. 516482) that acts as a potent, non-competitive, transition-state analog inhibitor of γ-secretase (K is = 15 nM and K ii = 32 nM in solubilized human γ-secretase; K is is the inhibition constant for inhibitor binding to the free enzyme and K ii is the inhibition constant for inhibitor binding to the Enzyme-Substrate complex).