JAK3 Inhibitor VIII, NSC114792 - Calbiochem
| Name | JAK3 Inhibitor VIII, NSC114792 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 420146 |
| Formula | C₂₆H₃₂N₄O₂S |
| Purity | ≥99% by HPLC |
| Description | A cell-permeable steroidal-purinethione compound that targets JAK3 kinase domain and selectively inhibits JAK3, but not JAK1, JAK2, or TYK2, activity in cell-free immuncomplex kinase assays, and effectively blocks the constitutive Jak3 and STAT5 phosphorylations (complete inhibition at 10 µM) in BaF3-JAK3 V674A and BLNK -/- BKO84 culltures |
| Supplier Page | Shop |
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