HIF-1 Inhibitor - CAS 934593-90-5 - Calbiochem

Name HIF-1 Inhibitor - CAS 934593-90-5 - Calbiochem
Supplier EMD Millipore
Catalog 400083
Cas Number 934593-90-5
Formula C₂₆H₂₉NO₅
Purity ≥98% by HPLC
Description A cell-permeable amidophenolic compound that inhibits hypoxia-induced HIF-1 transcription activity (IC 50 = 0.7 and 2.6 µM using AGS and Hep3B cells, respectively, in a reporter assay) by selectively blocking the hypoxia-induced accumulation of cellular HIF-1α protein, while exhibiting no apparent effect on the cellular level of HIF-1α mRNA or that of HIF-1β protein.
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