Flt-3 Inhibitor II - CAS 896138-40-2 - Calbiochem

Name Flt-3 Inhibitor II - CAS 896138-40-2 - Calbiochem
Supplier EMD Millipore
Catalog 343021
Cas Number 896138-40-2
Formula C₁₇H₁₂N₂O₃
Purity ≥95% by HPLC
Description A cell-permeable symmetrical indolylmethanone kinase inhibitor that is more selective toward Flt3 over PDGFR either in cell-based receptor autophosphorylation (IC 50 = 40 nM vs. 300 nM) or in cell-free kinase reactions (IC 50 = 33 nM vs. 171 nM) and potently induces apoptosis in Flt3-expressing primary AML patient blasts
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