Name | Flt-3 Inhibitor II - CAS 896138-40-2 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 343021 |
Cas Number | 896138-40-2 |
Formula | C₁₇H₁₂N₂O₃ |
Purity | ≥95% by HPLC |
Description | A cell-permeable symmetrical indolylmethanone kinase inhibitor that is more selective toward Flt3 over PDGFR either in cell-based receptor autophosphorylation (IC 50 = 40 nM vs. 300 nM) or in cell-free kinase reactions (IC 50 = 33 nM vs. 171 nM) and potently induces apoptosis in Flt3-expressing primary AML patient blasts |
Supplier Page | Shop |