Raf Kinase Inhibitor VI - CAS 331444-40-7 - Calbiochem
| Name | Raf Kinase Inhibitor VI - CAS 331444-40-7 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 553016 |
| Cas Number | 331444-40-7 |
| Formula | C₂₂H₂₂N₄O₃S |
| Purity | ≥95% by HPLC |
| Description | A purine-2,6-dione compound that targets the ATP-binding pocket of B-Raf and effectively inhibits the phosphorylation of MEK by wild-type B-Raf in cell-free in vitro kinase assays (IC 50 = 1.7 µM and K i , app = 106 nM with 100 µM ATP) |
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