BRPF1 BD Inhibitor - Calbiochem

Name BRPF1 BD Inhibitor - Calbiochem
Supplier EMD Millipore
Catalog 532718
Formula C₂₂H₂₆N₄O₃
Purity ≥98% by HPLC
Description A cell-permeable dimethyl-benzimidazolone compound that exhibits BRPF1-selective bromodomain (BD) affinity ( K d = 10 nM) by targeting the acetyl-lysine (KAc) pocket, while exhibiting much reduced or little affinity toward BDs from 34 other proteins, including bromodomain and PHD finger-containing (BRPF) family members BRPF2 (BRD1) and BRPF3 ( K d = 879 nM and 3.1 µM, respectively)
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