p21-Activated Kinase Inhibitor III, IPA-3 - CAS 42521-82-4 - Calbiochem
| Name | p21-Activated Kinase Inhibitor III, IPA-3 - CAS 42521-82-4 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 506106 |
| Cas Number | 42521-82-4 |
| Formula | C₂₀H₁₄O₂S₂ |
| Purity | ≥97% by HPLC |
| Description | A cell-permeable symmetrical disulfide allosteric inhibitor that selectively targets the autoregulatory domain of group I, but not group II, PAKs (p21-activated kinases) and prevents the activation of PAK1/2/3 (% inhibition= 95, 70, and 60, respectively, with 10 µM inhibitor; IC 50 = 2.5 µM for PAK1) |
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