Name | Bruton's Tyrosine Kinase Inhibitor III - CAS 936563-87-0 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 203661 |
Cas Number | 936563-87-0 |
Formula | C₂₅H₂₄N₆O₂ |
Purity | ≥98% by HPLC |
Description | A cell-permeable pyrrolopyridinyl-acryloyl compound that acts as a highly potent, selective, and irreversible inhibitor of BTK (IC 50 = 720 pM), while affecting Lyn, Lck, and Itk activity only at much higher concentrations (IC 50 = 14 nM, 97 nM, and 1.0 µM, respectively) |
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