Bruton's Tyrosine Kinase Inhibitor III - CAS 936563-87-0 - Calbiochem

Name Bruton's Tyrosine Kinase Inhibitor III - CAS 936563-87-0 - Calbiochem
Supplier EMD Millipore
Catalog 203661
Cas Number 936563-87-0
Formula C₂₅H₂₄N₆O₂
Purity ≥98% by HPLC
Description A cell-permeable pyrrolopyridinyl-acryloyl compound that acts as a highly potent, selective, and irreversible inhibitor of BTK (IC 50 = 720 pM), while affecting Lyn, Lck, and Itk activity only at much higher concentrations (IC 50 = 14 nM, 97 nM, and 1.0 µM, respectively)
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