Ketohexokinase Inhibitor - Calbiochem

Name Ketohexokinase Inhibitor - Calbiochem
Supplier EMD Millipore
Catalog 420640
Formula C₂₁H₂₆N₈S•2HCl
Purity ≥97% by HPLC
Description An orally bioavailable pyrimidinopyrimidine compound that acts as a potent, reversible and ATP-competitive inhibitor of human hepatic KHK activity (KHK-C isoform; IC 50 = 12 nM in a transcreener ADP assay) and efficiently blocks fructose-1-phosphate secretion (IC 50 ≤ 400 nM in HepG2 cells)
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