TLR3/dsRNA Complex Inhibitor - Calbiochem

• Supplier: EMD Millipore
• Catalog: 614310
• Formula: C₁₈H₁₃ClFNO₃S
• Purity: ≥99% by HPLC
• Description: A thiophenecarboxamidopropionate compound that acts as a direct, competitive and high affinity inhibitor of dsRNA binding to TLR3 (K i = 2.96 µM; K d = 19 nM for dsRNA binding to TLR3) and selectively antagonizes stimulated TLR3 signaling without affecting TLR1/2, TLR2/6, TLR4 and TLR7 pathways

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