DUB Inhibitor IV, b-AP15 - CAS 1009817-63-4 - Calbiochem
| Name | DUB Inhibitor IV, b-AP15 - CAS 1009817-63-4 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 662140 |
| Cas Number | 1009817-63-4 |
| Formula | C₂₂H₁₇N₃O₆ |
| Purity | ≥97% by HPLC |
| Description | A cell-permeable bis -nitrobenzylidene-piperidinone that inhibits 19S deubiquitinase (DUB) activity (IC 50 = 2.1 µM against Ub-AMC hydrolysis) in a reversible manner by directly targeting UCH37/UCH-L5 and USP14, while exhibiting little or no activity toward BAP1, UCH-L1, UCH-L3, USP2, USP7, USP8 (IC 50 >100 µM), or POH1/PRN11 |
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