R b/ R af-1 D isruptor 251
| Name | R b/ R af-1 D isruptor 251 |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 559270 |
| Cas Number | 72214-67-6 |
| Formula | C₈H₉Cl₃N₂S |
| Purity | ≥97% by HPLC |
| Description | A cell-permeable and orally active isothiouronium compound that potently and selectively disrupts the Rb/Raf-1 interaction (IC 50 = 77 nM in cell-free binding assays), while exhibiting no effect against Rb/B-Raf, Rb/E2F1, Rb/prohibitin, Rb/cyclin E, Rb/HDAC1, Raf-1/MEK1, or Raf-1/MEK2 interaction |
| Supplier Page | Shop |
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