TGF-β RI Kinase Inhibitor IV - CAS 909910-43-6 - Calbiochem
| Name | TGF-β RI Kinase Inhibitor IV - CAS 909910-43-6 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 616454 |
| Cas Number | 909910-43-6 |
| Formula | C₂₅H₁₉N₅S |
| Purity | ≥97% by HPLC |
| Description | A cell-permeable trisubstituted pyrazole compound that has been shown to selectively inhibit ALK-4/5/7-mediated (IC 50 = 45, 12, and 7.5 nM, respectively, in luciferase transcription activity assays), but not ALK-1/2/3/6-mediated cellular signaling in Mv1Lu R4-2 transfectants expressing the individual Type I TGF-β receptors |
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