AKR1C3 Inhibitor - Calbiochem
| Name | AKR1C3 Inhibitor - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 123855 |
| Formula | C₁₄H₁₀F₃NO₂ |
| Purity | ≥99% by HPLC |
| Description | A cell-permeable 3-phenyl-aminobenzoate compound that acts as a potent, competitive, reversible, active-site targeting inhibitor of aldo-keto reductase 1C3 (AKR1C3; type 5 17β-hydroxysteroid dehydrogenase) (IC 50 = 60 nM) with excellent selectivity over other closely related human AKR isoforms (IC 50 = 22.7, 15.4, 62.7, >50, and >50 µM for and AKR1C1, AKR1C2, AKR1C4, AKR1B1 and AKR1B10, respectively |
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