JNK Inhibitor XV, IQ-1S - Calbiochem

• Supplier: EMD Millipore
• Catalog: 420149
• Formula: C₁₅H₈N₃Ona
• Purity: ≥95% by HPLC
• Description: A cell-permeable indenoquinoxalinone-oxime (IQ) compound that acts as a potent, non-toxic, reversible, ATP-competitive, high-affinity inhibitor of JNK (K d = 390, 360 and 87 nM for JNK1, JNK2 and JNK3, respectively) with moderate selectivity over CK1δ, PI 3-Kγ, and MKNK2 (IC 50 = 1.4, 1.2, and 1.8 µM, respectively)

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